Translational Neuroscience


Our lab focuses on developing cell-based and gene-based therapies for neurodegenerative diseases. We use advanced methods, such as CRISPR/Cas9 for in vivo gene modification, and take advantage of multiple platforms for the delivery of therapeutics into the CNS, including mesenchymal stem cells, exosomes and peptides. Using cell cultures and animal models, we evaluate the effect of gene modification on cognition and behaviour, as well as on disease-related biochemical and histological features. 

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